|New York Yankees||1||0||0||1-0||W1||–|
|Toronto Blue Jays||1||0||0||1-0||W1||–|
|Boston Red Sox||0||1||1.0||0-1||L1||161|
|Tampa Bay Devil Rays||0||1||1.0||0-1||L1||161|
Twins 3, Orioles 2. The O’s dropped their second straight in Minnesota. One day after being bested by a Johan Santana, with less than his best stuff, Baltimore blew an early 2-0 lead and fell to a guy named Boof. Former Devil Ray Aubrey Huff had two hits for the second straight game and his second RBI.
- Bernie Williams called manager Joe Torre and several of his teammates before the opening day match up with the Rays. Bernie insists that he is not retired but that he would not play for any team other than the Yankees in 2007. Williams declined a minor league contract offer from the Yankees before the season began.
- The Red Sox send Josh Beckett to the mound against the Royals. Beckett won 16 in his first season with the Sox, but was considered a disappointment with 5.01 ERA. The Sox and Curt Schilling dropped the opener to Kansas City.
- Toronto will go with AJ Burnett as they try to take two straight in Detroit. Burnett won 10 games in his first season in Toronto, but missed two months.